PI3K: Missense mutation motivates malignancy
نویسندگان
چکیده
منابع مشابه
Malformation, Mutation and Malignancy
This lecture honours the memory of Edward Long Fox, a major figure in the proud tradition of Bristol medicine. His grandfather, Edward Long Fox senior, was a physican at the Infirmary as was his Uncle also; clearly there was a strong family tradition for him to live up to. Edward Long Fox junior was born in 1832, and educated at Bath and Shrewsbury before going up to Balliol College, Oxford. He...
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175 JGP | Research News The human heart beats more than 2.5 billion times over the course of an average lifetime. The ryanodine receptor type 2 (RyR2) helps regulate these beats, and mutations in this ion channel cause catecholamine-induced polymorphic ventricular tachycardia (CPVT). Uehara et al. describe how one particular disease-causing mutation dramatically affects RyR2 behavior (1). The a...
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ژورنال
عنوان ژورنال: Cancer Biology & Therapy
سال: 2004
ISSN: 1538-4047,1555-8576
DOI: 10.4161/cbt.3.8.1031